Anti-Desmin Antibody

Desmin is a 53 kDa class III intermediate filament protein that forms a critical part of the cytoskeleton in cardiac, skeletal, and smooth muscle, anchoring myofibrils at Z-discs and intercalated discs. This unconjugated polyclonal reagent from Antibodies.com was raised in rabbit and supports Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows on human, mouse, and rat samples. Investigators use desmin immunolabeling to chart myogenic differentiation in stem-cell cultures, to map muscle architecture in tissue sections, and to flag rhabdomyosarcoma, leiomyosarcoma, and other soft-tissue tumors of muscle origin in pathology workups. The antibody ships as 100 µl of liquid, and the unconjugated format lets labs pair it with their own secondary reagents for fluorescence or chromogenic detection.