Anti-Deoxycytidine kinase Antibody

Produced by Antibodies.com as an unconjugated polyclonal reagent, this rabbit antibody recognizes Deoxycytidine kinase (DCK), the rate-limiting enzyme that catalyzes the first phosphorylation step of deoxycytidine and related deoxyribonucleosides within the nucleotide salvage pathway. Each vial contains 100 µL of antibody validated for Western blot and immunofluorescence applications on human samples. DCK activity is central to the intracellular activation of nucleoside analog prodrugs such as gemcitabine and cytarabine, making this reagent a useful marker in studies of chemotherapy response, tumor nucleotide metabolism, mitochondrial dNTP supply, and resistance mechanisms in hematological and solid tumor models. The polyclonal format provides broader epitope coverage than monoclonal alternatives, supporting consistent detection of endogenous kinase levels across varied lysate preparations and clearer visualization of subcellular distribution by IF. For best results, store refrigerated, aliquot upon receipt to limit repeated freeze-thaw cycles, and protect from light when planning downstream fluorescent labeling workflows.