Anti-DEFB1 Antibody

Raised in rabbit and supplied by Antibodies.com as an unconjugated polyclonal reagent, this antibody targets human beta-defensin 1 (DEFB1), a 36-amino-acid antimicrobial peptide expressed by epithelial cells of the skin, respiratory tract, gastrointestinal lining, and urinary tract. The reagent is formatted for Western Blot detection and recognizes the defensin precursor and mature peptide across multiple epitopes, supporting consistent signal in lysate-based assays of cultured epithelial and immune cells.

Each vial is supplied at 1 mg/ml in phosphate buffered saline (PBS), pH 7.2, with 0.05% sodium azide as a preservative, and ships in a 100 µl volume suitable for multiple blotting experiments. The unconjugated format lets researchers pair the antibody with their preferred HRP- or fluorophore-conjugated secondary reagents, fitting both chemiluminescent and fluorescent detection workflows.

Validated reactivity covers human, mouse, and rat samples, making the antibody useful for comparative studies of mucosal and innate immunity in translational research, including characterization of DEFB1 expression in inflammatory skin disorders, cystic fibrosis airway epithelium, inflammatory bowel disease tissue, and urinary tract infection models. Store refrigerated; protect from light and avoid repeated freeze-thaw cycles to preserve antibody integrity for downstream analysis.