Anti-DDX58 Antibody

This Rabbit polyclonal reagent from Antibodies.com targets the DDX58 protein, also known as RIG-I, a cytoplasmic DExD/H-box RNA helicase that plays a central role in innate antiviral immunity by sensing viral dsRNA and triggering type I interferon signalling. The antibody is supplied as a 50 µl aliquot at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, is unconjugated, and belongs to the IgG isotype. It has been validated for use in Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows, and it is reactive with human samples, making it well suited to studies of endogenous RIG-I expression in cultured cells and tissue sections. The reagent is affinity purified from rabbit host serum, carries an estimated purity above 95%, and should be stored at -20 °C in working aliquots to limit freeze/thaw damage, with short-term handling at 4 °C. Provided under the A30070 product family as a 50 µl format, this polyclonal DDX58 antibody from Antibodies.com is intended for research use only and supports investigations into viral RNA recognition, IRF3/NF-κB pathway activation, and broader RIG-I-related innate immune mechanisms.