Anti-DDX4 Antibody

DDX4, also known as VASA, is an ATP-dependent RNA helicase that serves as a conserved marker of germline cells in humans, with strong expression in the ovary and testis. This rabbit polyclonal antibody from Antibodies.com is raised against DDX4 and validated for Western blot (WB) and immunohistochemistry (IHC) workflows, supporting studies of primordial germ cell development, spermatogenesis, oogenesis, and germline stem cell biology.

Supplied as an unconjugated reagent in a 100 µl vial, it is intended for use on fixed tissue sections and protein extracts where the localization and abundance of DDX4 can be tracked across developmental stages. The polyclonal format increases the range of epitopes recognized within the DDX4 protein, which is useful when probing for isoform-level differences or when working with samples where a single monoclonal epitope may be masked.

Researchers studying reproductive biology, germ cell tumours, or pluripotent stem cell differentiation often rely on DDX4 immunostaining to confirm successful germline specification in their model systems, and a human-reactive primary antibody provides a reliable signal in both paraffin-embedded and fresh-frozen sections prepared from reproductive tissues.