Anti-DDX21 Antibody

A rabbit polyclonal antibody from Antibodies.com targets the DEAD-box RNA helicase DDX21, a nucleolar protein involved in ribosomal RNA biogenesis and innate antiviral signaling. Supplied as 100 µl at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated reagent is validated for Western blot, immunohistochemistry, and immunofluorescence on fixed sections and cultured human cells. DDX21 localizes predominantly to the nucleolus, where it supports rRNA transcription and processing, and it redistributes to the cytoplasm during viral infection to act as a sensor of foreign nucleic acids. Laboratories working on ribosome biogenesis, RNA metabolism, stress granule assembly, or host-pathogen interactions can apply this reagent to detect endogenous DDX21 in whole-cell lysates, paraffin-embedded tissue, and adherent cell lines. The polyclonal format recognizes multiple epitopes on the target, supporting consistent signal across a variety of sample preparations, and the 50% glycerol formulation is convenient for freezer storage at -20 °C while resisting repeated freeze-thaw cycles.