Anti-DDX1 Antibody

Produced in rabbit as an unconjugated polyclonal antiserum, this reagent targets the DEAD-box helicase DDX1, an ATP-dependent RNA helicase of approximately 82 kDa that participates in mRNA splicing, transcriptional regulation, and the DNA damage response. The antibody recognizes an epitope conserved across human, mouse, and rat DDX1 sequences, allowing parallel studies in multiple model systems and supporting western blot detection of the endogenous protein as well as immunohistochemistry on fixed tissue sections. It is supplied by Antibodies.com as 100 µl of a 1 mg/ml solution in PBS, buffered with 0.1% sodium azide as preservative and 50% glycerol for cryoprotection, and aliquoted for repeated bench use without freeze-thaw damage. DDX1 has been investigated as a candidate marker in hepatocellular carcinoma and as a host factor that facilitates HIV-1 Rev-mediated RNA export, so this reagent serves labs working on viral replication, RNA processing, or cancer signaling pathways. Store the vial at -20 °C in working aliquots to preserve antibody activity and limit repeated freeze-thaw cycles.