Anti-DDAH2 Antibody

This unconjugated rabbit polyclonal antibody targets DDAH2 (dimethylarginine dimethylaminohydrolase 2), an enzyme that hydrolyzes asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase. Supplied by Antibodies.com at 100 µl per vial, the reagent is validated for western blot and immunofluorescence workflows and recognizes the target in human, mouse, and rat samples. Investigators studying endothelial nitric oxide signaling, cardiovascular pathophysiology, and methylarginine metabolism use this reagent to track DDAH2 abundance in cultured cells, tissue lysates, and fixed sections. The polyclonal format provides broader epitope coverage than a monoclonal reagent, which is helpful when comparing DDAH2 expression across disease models of vascular dysfunction, insulin resistance, and inflammatory challenge. DDAH2 is also studied as a candidate regulator of asymmetric dimethylarginine clearance, so the antibody is commonly paired with ADMA measurements to connect protein expression with functional readouts. Working dilutions should be optimized empirically for the chosen detection chemistry and sample preparation. For handling, keep the antibody refrigerated and protected from light, and prepare working aliquots to minimize freeze-thaw cycles of the stock solution.