Anti-DCP1A Antibody

This Rabbit polyclonal reagent from Antibodies.com targets DCP1A (Decapping mRNA 1A), the scaffolding subunit of the mRNA decapping complex that removes the 7-methylguanosine cap from eukaryotic transcripts to drive 5'-to-3' mRNA decay, nonsense-mediated decay, and stress granule assembly. The unconjugated antibody is supplied as 100 µl of polyclonal serum and is validated for Western blot and immunohistochemistry on human samples, where it produces a band near 75 kDa in cell lysates and a cytoplasmic staining pattern that co-localizes with established P-body markers including EDC4 and DCP2.

Packaged in a single-use vial, the antibody is compatible with standard chromogenic IHC, fluorescence IHC, and immunoblotting workflows using HRP- or fluorophore-conjugated secondary reagents, and is intended for research use only. Researchers investigating post-transcriptional gene regulation, P-body dynamics, or DCP1A involvement in tumor biology can combine this reagent with siRNA or CRISPR knock-down controls to validate decapping complex integrity in cultured human cell lines and in formalin-fixed paraffin-embedded tissue sections.