Anti-DCLRE1C Antibody

Manufactured by Antibodies.com, this Rabbit polyclonal reagent is raised against recombinant human DCLRE1C (also known as Artemis, A-SCID, SCIDA, and SNM1C), the DNA cross-link repair 1C protein implicated in V(D)J recombination and non-homologous end joining. The antibody is supplied as an unconjugated IgG at 1.0 mg/mL in a 50 µL aliquot, purified by affinity chromatography against the immunogen and formulated in phosphate-buffered saline (pH 7.4) containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol, with no Mg²⁺ or Ca²⁺ present. It is shipped at 4 °C and should be aliquoted upon arrival for long-term storage at –20 °C, with repeated freeze/thaw cycles avoided to preserve activity. Validated for Western blotting (WB), immunohistochemistry (IHC) and immunocytochemistry/immunofluorescence (ICC/IF), the polyclonal antibody detects the endogenous total DCLRE1C protein across human, mouse and rat samples, making it suitable for comparative studies of DNA damage response and lymphoid development. This research-use-only reagent from Antibodies.com provides a reliable tool for laboratories investigating artemis-deficient SCID, NHEJ pathway function and related genomic stability questions.