Anti-DCLRE1B Antibody

A rabbit polyclonal IgG reagent from Antibodies.com targets the DNA cross-link repair nuclease DCLRE1B, also known as SNM1B and Apollo. This 5'-3' exonuclease participates in interstrand cross-link repair, contributes to telomere maintenance through its interaction with shelterin components, and supports the S-phase DNA damage response in replicating cells, making the antibody relevant for studies of genomic stability, replication stress, and chromosome end protection.

Supplied as 100 µl of unconjugated antibody in a single vial, the reagent is validated for western blot detection of the endogenous protein in human and mouse samples. The polyclonal format and IgG isotype are compatible with standard HRP- or fluorescent-labelled secondary antibodies and standard chemiluminescent detection workflows used in research labs. Researchers can apply the reagent to whole-cell lysates or tissue extracts to investigate DCLRE1B expression across cell lines and primary samples, supporting work on DNA repair pathways, telomere biology, and cellular responses to genotoxic stress.

Refrigerated storage upon arrival is recommended, with aliquoting advised for longer term use to limit freeze-thaw cycles and preserve binding activity. Each vial is intended for research use only and provides a reliable antibody tool for probing DCLRE1B levels in cell biology and DNA damage studies.