Anti-DCC Antibody

This rabbit polyclonal antibody recognizes the DCC receptor, a transmembrane dependence receptor originally identified as Deleted in Colorectal Carcinoma that serves as the principal receptor for the axon guidance cue netrin-1. The reagent, supplied by Antibodies.com in unconjugated format, is validated for Western Blot, Immunofluorescence, and ELISA applications and shows reactivity with Human, Mouse, and Rat samples, supporting research into nervous system development, enteric innervation, and tumor suppressor pathways where DCC-mediated signaling influences cell migration and apoptosis.

Shipped as 100 µl of liquid stock, the polyclonal antibody is produced in Rabbit and contains no fluorophore or enzyme conjugation, allowing researchers to pair it with their preferred secondary antibody for immunofluorescence staining on fixed cells and tissue sections, western blot detection of endogenous DCC protein in cell lysates and tissue homogenates, or ELISA-based quantification. The unconjugated format also supports chromogenic detection strategies, custom biotinylation, and amplified readouts when downstream labeling is required for sensitive detection of low-abundance DCC expression in neuronal and epithelial model systems.