Anti-DAAM1 Antibody

This polyclonal antibody from Antibodies.com targets DAAM1 (Dishevelled-Associated Activator of Morphogenesis 1), a formin-family protein that regulates actin cytoskeleton dynamics through the Wnt/planar cell polarity (PCP) signaling cascade. Raised in rabbit and supplied unconjugated in a 100 µl vial, the reagent is validated for western blot and immunohistochemistry workflows and cross-reacts with human and mouse samples. DAAM1 nucleates linear actin filaments via its FH1 and FH2 domains and is studied in contexts including directed cell migration, gastrulation morphogenesis, neurite outgrowth, and cytoskeletal remodeling in metastatic tumor models. Researchers investigating PCP pathway components, formin-mediated actin assembly, or Rho-GTPase-coupled cytoskeletal control use this reagent to probe endogenous DAAM1 expression in lysates and fixed tissue sections. The polyclonal format recognizes multiple epitopes on the full-length target, supporting detection across denatured and native conditions in standard SDS-PAGE and formalin-fixed paraffin-embedded preparations. Aliquot upon first use and store refrigerated for stability across repeated experiments; for research use only.