Anti-D-dimer Antibody

D-dimer is the terminal fibrin degradation fragment released when cross-linked fibrin is cleaved by plasmin during fibrinolysis, and its circulating concentration is widely studied in research programmes focused on venous thromboembolism, pulmonary embolism, disseminated intravascular coagulation, sepsis-associated coagulopathy, and fibrin turnover kinetics. The Mouse monoclonal Anti-D-dimer Antibody from Antibodies.com is supplied as a Protein A purified IgG1 reagent in a 1 mg vial, unconjugated and intended for ELISA and Western blot workflows in primary antibody research.

The clone recognises the D-dimer neoepitope generated through plasmin-mediated cleavage of cross-linked fibrin, which allows investigators to distinguish true fibrin-specific breakdown products from intact fibrinogen or fibrin monomer. The reagent can be applied to cell lysates, tissue extracts, and purified protein preparations, supporting quantitative immunoassay development and qualitative band identification on Western blot membranes under reducing or non-reducing conditions.

Recommended handling: store the vial at -20 °C, protect from light, and aliquot upon first use to limit freeze-thaw cycles. Short-term working aliquots may be kept refrigerated between experimental sessions. The product is supplied in a single-use vial and is intended for in vitro research use only.