Anti-Cytomegalovirus (CMV-IE1/2) Antibody

The Antibodies.com mouse monoclonal reagent targets the Immediate Early 1 and Immediate Early 2 (IE1 and IE2) gene products of Human Cytomegalovirus, the principal transcriptional activators expressed during the earliest phase of the viral replication cycle. These immediate-early proteins drive downstream viral gene expression and serve as sensitive indicators of active CMV infection in cell-based experimental systems.

Provided as a Protein G purified, unconjugated IgG1(k) monoclonal antibody in a 500 µg vial, this clone is validated for Western blot and immunofluorescence assay (IFA) workflows. Typical research applications include monitoring IE1/IE2 expression kinetics in permissive fibroblast cultures, investigating viral latency and reactivation mechanisms, and characterizing immune-evasion pathways relevant to transplant virology and congenital CMV studies.

The host species is mouse, and the reagent is intended for research use only, supporting detection across infected cell lysate preparations, fixed-cell imaging, and recombinant antigen platforms used in herpesvirus laboratory research.