Anti-Cytokeratin 7 (N-terminus) Antibody

This unconjugated mouse monoclonal antibody from Antibodies.com targets the N-terminal region of human Cytokeratin 7 (KRT7), a ~54 kDa type II intermediate filament protein expressed in glandular and transitional epithelia. The reagent is supplied as 50 µl of purified IgG in 0.1 M Tris-glycine buffer (pH 7.4) with 150 mM NaCl, 0.2% sodium azide, and 50% glycerol for storage stability.

Validated for western blot and immunocytochemistry, the antibody detects Cytokeratin 7 in human samples and supports tumor pathology workflows that distinguish CK7-positive adenocarcinomas of lung, breast, ovarian, endometrial, pancreatic, and biliary origin from CK7-negative tumors such as most colorectal carcinomas. The N-terminal epitope location allows recognition of full-length KRT7 and commonly studied isoforms, while the unconjugated format permits flexible pairing with user-selected secondary labels for immunofluorescence or chromogenic ICC.

Storage at -20 °C is recommended; the glycerol-containing formulation protects against repeated freeze-thaw cycles, and sodium azide serves as a microbial preservative.