Anti-Cytokeratin-7 Antibody

This unconjugated monoclonal reagent from Antibodies.com targets Cytokeratin-7, a ~51 kDa type II keratin expressed in glandular and transitional epithelia. Produced in mouse hosts as IgG1, the antibody is supplied at 100 µl in a vial containing TBS buffer (pH 7.4) supplemented with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative.

Validated for Western blot and immunohistochemistry on human samples, the reagent is widely used as a diagnostic immunohistochemical marker for differential tumor diagnosis. Researchers rely on it to distinguish CK7-positive ovarian, lung, and breast adenocarcinomas from CK7-negative colorectal and renal carcinomas, and to identify mesothelial origin in effusion cytology. Its reactivity has been characterized against human tissue, supporting epithelial cancer pathology studies, biomarker validation, and characterization of glandular epithelial differentiation in developmental and regenerative research.

The unconjugated format offers flexibility for pairing with HRP, biotin, or fluorophore-conjugated secondary reagents of the researcher's choice. Storage recommendations call for standard freezer conditions to preserve antibody stability, with aliquoting advised to limit repeated freeze-thaw cycles on working stocks.