Anti-Cytokeratin 18 (T410) Antibody

This rabbit polyclonal reagent from Antibodies.com targets a specific phosphorylated epitope on Cytokeratin 18 (CK18), namely the threonine residue at position 410. CK18 is a type I intermediate filament protein broadly expressed in simple epithelia, and phosphorylation at T410 is a recognized biochemical marker linked to caspase-mediated cleavage during apoptosis, making this antibody a useful tool for studying epithelial cell death, tumor progression, and cytoskeletal remodeling.

The antibody is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, in a 50 µl vial. It is unconjugated and validated for Western blot, immunohistochemistry, and immunofluorescence workflows, with demonstrated reactivity across human, mouse, and rat samples. Store refrigerated to preserve activity, and protect from light to maintain the sodium azide-stabilized formulation.