Anti-Cytokeratin 18 (S48) Antibody

Produced in rabbit as an unconjugated polyclonal reagent, this primary antibody targets the type I intermediate filament protein Cytokeratin 18 and is validated for western blot, immunohistochemistry, and immunofluorescence workflows. Provided as a 100 µl vial at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.2, it recognizes the target in human and mouse samples, supporting research on epithelial cell identity, hepatocyte biology, and epithelial-derived tumor models where cytokeratin 18 serves as a lineage marker. Store frozen in working aliquots to limit freeze-thaw cycles of the stock solution. Investigators studying caspase-mediated cytokeratin 18 cleavage during apoptosis, circulating tumor cell detection, or epithelial-mesenchymal transition can apply the reagent to formalin-fixed paraffin-embedded tissue sections, cultured epithelial cell monolayers, and standard immunoblots of epithelial lysates. Antibodies.com supplies the antibody for direct use with secondary detection reagents chosen by the end user.