Anti-Cytochrome P450 4A11 Antibody

This unconjugated polyclonal antibody from Antibodies.com targets Cytochrome P450 4A11 (CYP4A11), a microsomal monooxygenase expressed chiefly in human liver and kidney, where it catalyzes the ω-hydroxylation of medium-chain fatty acids such as lauric and myristic acid. The enzyme contributes to 20-hydroxyeicosatetraenoic acid (20-HETE) synthesis, an eicosanoid pathway that regulates vascular tone and has been linked in genetic studies to essential hypertension.

Provided as 100 µl of rabbit host reagent, it is validated for Western blot, immunohistochemistry, and immunofluorescence workflows against human samples. Laboratories studying hepatic fatty-acid metabolism, renal physiology, eicosanoid signaling, or hypertension-associated CYP4A11 polymorphisms use this reagent to map protein distribution across tissue sections and confirm expression in cell-based models.

The polyclonal format offers broad epitope coverage, useful when probing variants or processed forms of the CYP4A11 enzyme, and the unconjugated presentation allows downstream pairing with custom reporter tags or secondary detection systems tailored to individual assay designs.