Anti-Cytochrome c oxidase subunit 6A1, mitochondrial Antibody

The polyclonal antibody from Antibodies.com targets the nuclear-encoded mitochondrial cytochrome c oxidase subunit 6A1 (COX6A1), a transmembrane component of respiratory chain complex IV. Raised in rabbit and supplied unconjugated at 100 µg per vial, this reagent is validated for western blot (WB) and immunohistochemistry (IHC) applications on human samples.

COX6A1 contributes to the terminal oxidase of oxidative phosphorylation, transferring electrons from cytochrome c to molecular oxygen and helping establish the proton gradient that drives ATP synthesis. Research applications include studies of mitochondrial biogenesis, complex IV assembly in mammalian tissues, oxidative phosphorylation deficiency, and respiratory supercomplex organization.

The polyclonal format allows recognition of multiple epitopes on the mature subunit, supporting robust signal on denatured lysates in WB and on fixed, paraffin-embedded tissue sections in IHC. The antibody is shipped refrigerated; upon receipt, aliquot and store at -20°C for long-term use, avoiding repeated freeze-thaw cycles. Each lot is quality-controlled to confirm selective binding to the human COX6A1 target.