Anti-CYTH2 Antibody

CYTH2 (Cytohesin-2), also known as ARNO, is a guanine nucleotide exchange factor that activates ARF family GTPases and regulates cell adhesion, membrane trafficking, and receptor signaling at the plasma membrane. This unconjugated rabbit polyclonal IgG reagent from Antibodies.com targets CYTH2 across human, mouse, and rat samples, and is validated for Western blot detection of the endogenous protein and immunofluorescence imaging of its subcellular localization. Supplied as a 50 µl aliquot, the polyclonal format recognizes multiple epitopes on cytohesin-2, supporting consistent labeling in cell extracts and fixed-cell preparations derived from a range of tissues. Researchers studying integrin signaling, Golgi-to-plasma-membrane transport, or ARF-mediated cytoskeletal remodeling commonly use this reagent to map CYTH2 expression, confirm its recruitment to membrane ruffles, and probe interactions with binding partners such as GRASP and ARF1.