Anti-CyPA Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets cyclophilin A (CyPA), an 18 kDa peptidyl-prolyl cis-trans isomerase encoded by the PPIA gene that functions as the intracellular receptor for cyclosporine A. CyPA is widely expressed in the cytoplasm of human, mouse, and rat tissues, where it contributes to protein folding, inflammatory signaling cascades, and viral entry pathways including HIV-1 capsid recognition. The unconjugated reagent is supplied as a 100 µl liquid vial and has been validated for western blot and ELISA workflows, with reactivity confirmed against human, mouse, and rat samples. Researchers apply this reagent to investigate CyPA abundance and post-translational modification in cell lysates, tissue homogenates, and recombinant protein preparations. Polyclonal antibodies recognize multiple epitopes on the target, offering broader recognition than monoclonal reagents and making this format practical for studies across diverse model systems. For handling, aliquot upon first opening to limit repeated freeze-thaw cycles, and store refrigerated between uses; the product is intended for research use only.