Anti-CYP51A1 Antibody

Manufactured by Antibodies.com, this Rabbit polyclonal reagent targets CYP51A1, the lanosterol 14-alpha demethylase enzyme also known as CYP51, CYPLI, LDM, or Cytochrome P450 51A1. The antibody was raised against a recombinant human CYP51A1 immunogen and affinity-purified using the immunogen to deliver specificity for the endogenous target. Supplied as a 50 µl aliquot at 1.0 mg/mL in phosphate-buffered saline (pH 7.4, 150 mM NaCl) containing 0.02% sodium azide and 50% glycerol, the unconjugated polyclonal reagent is validated for Western blot (WB) and immunofluorescence (IF) applications. It cross-reacts with human, mouse, and rat samples, making it well suited for comparative studies of sterol biosynthesis and cytochrome P450 function across species. The host species is Rabbit, the clonality is polyclonal, and the conjugate is unconjugated, allowing users flexibility in choosing their own secondary detection chemistry. Recommended storage is at -20 °C, with aliquoting upon receipt advised to minimise freeze/thaw cycles and preserve activity. Synonyms listed for the target include CYP51, CYPLI, Cytochrome P450-14DM, Cytochrome P45014DM, Cytochrome P450LI, Sterol 14-alpha demethylase, and LDM, reflecting the enzyme's central role in sterol metabolism. Suitable anti-rabbit IgG secondary antibodies are available separately to support downstream detection. This product is intended for research use only and is not approved for diagnostic or therapeutic applications.