Anti-CYP4F2 Antibody

A rabbit polyclonal reagent from Antibodies.com targeting the cytochrome P450 4F2 enzyme, this unconjugated primary antibody is validated for western blot, immunohistochemistry, immunocytochemistry, and immunoprecipitation across human, mouse, and rat samples. CYP4F2 is a microsomal ω-hydroxylase that metabolizes vitamin E (tocopherols and tocotrienols), arachidonic acid, and various xenobiotics; common polymorphisms such as rs2108622 (V433M) influence warfarin dose requirements and circulating vitamin E status, which makes reliable protein-level detection valuable for pharmacogenomics, hepatic physiology, and nutrition research.

The antibody is supplied as 100 µl at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide, approximately pH 7.2, ready to use in standard immunodetection workflows. Researchers can apply it to lysates and fixed sections in cell culture and tissue models, and short-term store at 4 °C; for longer shelf life, aliquot and freeze at -20 °C, avoiding repeated freeze-thaw cycles. The broad species reactivity makes it useful for comparative studies of CYP4F2 expression in hepatic, renal, and extrahepatic tissues.