Anti-CYP46A1 Antibody

CYP46A1 (cytochrome P450 family 46 subfamily A member 1), also known as cholesterol 24-hydroxylase, is a brain-enriched enzyme that converts cholesterol into 24S-hydroxycholesterol, the principal route for cholesterol elimination from the central nervous system. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against CYP46A1 and validated for Western blot (WB) and immunohistochemistry (IHC) on human samples. Supplied at 100 µl per vial, the antibody supports studies of neurodegenerative disease, cholesterol homeostasis, and brain lipid metabolism. Researchers commonly apply it to characterize CYP46A1 expression in neuronal and glial cell populations, investigate links to Alzheimer's disease pathology, and probe sterol turnover across brain tissue lysates and fixed sections.