Anti-CYP3A4 Antibody

CYP3A4 is a member of the cytochrome P450 enzyme superfamily that mediates oxidative metabolism of a broad spectrum of xenobiotics and endogenous substrates in hepatic and intestinal tissue. This Antibodies.com rabbit polyclonal reagent was raised against CYP3A4 and supplied as an unconjugated preparation in a 100 µl vial, giving researchers flexibility to pair it with secondary reagents of their choice. The antibody is validated for Western blot analysis of CYP3A4 protein expression in cell lysates and for immunohistochemistry on formalin-fixed tissue sections, with confirmed reactivity toward both human and mouse samples. Investigators working on drug-drug interactions, hepatic pharmacology, or xenobiotic clearance can use this reagent to probe CYP3A4 expression across model systems and patient-derived specimens. Polyclonal clonality supports recognition of multiple epitopes on the target, which is helpful when isoform variation or post-translational modification of the enzyme is a concern.