Anti-CYP2E1 Antibody

Raised in rabbit against the cytochrome P450 2E1 (CYP2E1) enzyme, this polyclonal primary antibody from Antibodies.com targets a phase-I xenobiotic-metabolising protein best known for hepatic oxidation of ethanol, acetaminophen, and a broad spectrum of low-molecular-weight drugs and environmental toxicants. The unconjugated reagent is validated for western blot, immunohistochemistry, and immunofluorescence on human, mouse, and rat samples, supporting toxicology, hepatology, and drug-metabolism studies where CYP2E1 induction is being monitored.

The antibody is supplied as 100 µl of a 1 mg/ml stock formulated in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, allowing refrigerated storage and protection from microbial contamination. Because CYP2E1 epitopes are well conserved across the listed species, the polyclonal format increases the chance of recognising both linear and conformational determinants, and the reagent is readily paired with HRP- or fluorophore-conjugated secondary antibodies for chemiluminescent western blot or fluorescence imaging workflows.