Anti-CYP2E1 Antibody

Raised in rabbit as a polyclonal reagent, this unconjugated antibody targets cytochrome P450 2E1 (CYP2E1), a hepatic microsomal enzyme central to xenobiotic and ethanol metabolism and frequently studied in pharmacology and toxicology research. The preparation is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotective agent, in a 100 µl vial suitable for multiple immunoblotting runs. Validated applications include Western blot for protein-level expression profiling across hepatic and extrahepatic tissues, and immunocytochemistry (ICC) for subcellular localization studies. Demonstrated reactivity encompasses human, mouse, and rat samples, enabling cross-species comparative work on drug-induced enzyme regulation, acetaminophen bioactivation, and oxidative stress responses. From Antibodies.com, this CYP2E1 antibody is intended for research use only and serves laboratories investigating cytochrome P450-mediated biotransformation pathways.