Anti-CYP2C9 Antibody

The CYP2C9 enzyme is a key member of the cytochrome P450 family, primarily expressed in hepatic tissue where it drives the oxidative metabolism of numerous clinically prescribed drugs including warfarin, phenytoin, and tolbutamide. This unconjugated rabbit polyclonal antibody from Antibodies.com targets CYP2C9 for detection in human and mouse samples, supporting pharmacogenomics research, drug metabolism studies, and investigations of hepatic function.

The reagent is supplied as a 50 µl vial of liquid formulation, raised in rabbit host and purified to retain IgG isotype specificity. It has been validated for western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) workflows, supporting both protein expression profiling across cell lines and tissue sections, and subcellular localization studies focused on the endoplasmic reticulum compartment where CYP2C9 normally resides.

Recommended for research use only, this antibody detects endogenous CYP2C9 in hepatocellular preparations and in transfected overexpression systems, and is compatible with standard immunoblotting along with chromogenic or fluorescent detection chemistries. Storage at -20 °C in working aliquots minimizes freeze-thaw cycles and preserves titer across repeated experimental runs.