Anti-CYP2B6 Antibody

This rabbit polyclonal antibody targets human CYP2B6, a cytochrome P450 family 2 subfamily B member 6 enzyme that plays a central role in hepatic xenobiotic and drug metabolism, including the oxidative bioactivation of clinically relevant substrates such as bupropion, efavirenz, cyclophosphamide, and several antiretroviral and antineoplastic agents. Raised in rabbit and supplied as an unconjugated immunoglobulin preparation, the reagent is validated for Western blot and immunohistochemistry workflows, supporting studies of hepatic drug clearance, pharmacogenomics, and toxicology research.

The antibody is reactive with human CYP2B6 and is provided at 100 µL per vial, sufficient for multiple blotting and staining experiments. Investigators examining inter-individual variability in drug response, hepatic enzyme induction, pesticide metabolism, or chemotherapeutic resistance commonly use this reagent to probe CYP2B6 protein levels in liver tissue sections, cultured hepatocyte lysates, and recombinant expression systems. The unconjugated format enables flexible pairing with secondary antibodies and custom detection chemistries such as HRP, biotin, or fluorophore conjugates selected by the end user.

Each lot is supplied by Antibodies.com with supporting documentation for reproducible performance in Western blot and IHC applications against human samples, making the antibody a practical tool for laboratories characterizing CYP2B6 expression in translational pharmacology and liver-focused research projects.