Anti-CYP2B6 Antibody

This rabbit polyclonal IgG reagent targets cytochrome P450 2B6, a hepatic drug-metabolizing enzyme responsible for oxidation of clinically important substrates including bupropion, efavirenz, and cyclophosphamide. Supplied as 100 µl of unconjugated liquid stock, the antibody is validated for Western blot and immunohistochemistry workflows.

Cross-reactivity is reported on human, mouse, and rat samples, supporting studies of interspecies differences in xenobiotic metabolism. Researchers use this reagent to profile CYP2B6 expression in liver microsomes, tumor xenografts, and fixed tissue sections where P450 induction or suppression is being investigated, including pharmacokinetic and toxicology screens.

Antibodies.com ships the antibody refrigerated; aliquot upon arrival and avoid repeated freeze-thaw cycles to preserve binding activity. Brief centrifugation before opening recovers full volume from the vial. For research use only; not intended for diagnostic or therapeutic procedures.