Anti-CYP2A7 Antibody

CYP2A7 belongs to the cytochrome P450 family of monooxygenases, enzymes that catalyze oxidative transformation of xenobiotics, therapeutic drugs, and endogenous substrates, with primary expression reported in hepatic tissue.

The Anti-CYP2A7 Antibody from Antibodies.com is a rabbit polyclonal reagent supplied as 100 µl of liquid at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide, pH approximately 7.2, and is unconjugated, allowing flexible labelling in downstream assays.

Validated applications include Western blot (WB), immunohistochemistry (IHC), and immunocytochemistry (ICC), covering protein detection across denatured, fixed section, and cultured cell preparations. The antibody shows reactivity against Human, Mouse, and Rat samples, supporting comparative studies of CYP2A7 expression between human tissue and common preclinical model systems.

This reagent supports research into drug metabolism, xenobiotic processing, and the biology of the CYP2A subfamily, including work that distinguishes CYP2A7 from the closely related CYP2A6 isoform and from CYP2A13, both of which share substantial sequence homology within the active site region.