Anti-CYP19A1 Antibody

Aromatase, the protein product of the CYP19A1 gene, is a cytochrome P450 superfamily member that catalyzes the rate-limiting step in estrogen biosynthesis, converting androgens into estrone and estradiol. The enzyme sits at the center of steroidogenesis research and is studied in reproductive biology, placental function, granulosa-cell differentiation, and estrogen-receptor-positive cancer biology.

From Antibodies.com, this unconjugated rabbit polyclonal reagent is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial. Validated applications include western blot, immunohistochemistry, and immunoprecipitation, with confirmed reactivity against human, mouse, and rat aromatase. This three-species coverage and the polyclonal format, which recognizes multiple epitopes on the target, support comparative work between rodent models and human tissue samples, including studies of post-translationally modified enzyme or tissue-specific isoforms.

The unconjugated presentation leaves secondary detection fully customizable, so HRP, biotin, or fluorophore conjugates can be paired to match each assay. Sodium azide is included as a preservative; azide-sensitive downstream steps such as live-cell labeling or amine-reactive conjugation chemistries benefit from a quick buffer exchange before use. For routine short-term use, refrigerate the vial; for longer-term storage, aliquot and freeze to limit repeated freeze-thaw cycles.