Anti-CYP11A1 Antibody

This polyclonal reagent targets CYP11A1 (P450scc), the mitochondrial cholesterol side-chain cleavage enzyme that catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in steroid hormone biosynthesis. Raised in rabbit and supplied by Antibodies.com as 50 µl at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated antibody is validated for western blot (WB) and immunocytochemistry (ICC) applications across human, mouse, and rat samples. Researchers studying adrenal steroidogenesis, gonadal function, placental hormone production, and related disease models use this reagent to localize and quantify CYP11A1 expression in cell lines and primary tissue. For best results, store the vial at -20°C, avoid repeated freeze-thaw cycles, and aliquot upon first thaw to preserve antibody activity through extended studies.