Anti-CYCS Antibody

This Mouse monoclonal antibody specifically targets cytochrome c (CYCS), a small heme-containing protein that resides in the mitochondrial intermembrane space and serves dual roles in oxidative phosphorylation and the intrinsic apoptosis pathway. Produced by Antibodies.com as an unconjugated reagent supplied in a 100 µL vial, the antibody recognizes the somatic isoform across human, mouse, and rat samples, supporting translational work in cell line, primary tissue, and animal model systems. Validated for Western blot and immunohistochemistry applications, it enables detection of cytochrome c release during programmed cell death, assessment of mitochondrial content in tissue sections, and studies of respiratory chain integrity in models of neurodegeneration, ischemia-reperfusion injury, and tumor chemoresistance. The monoclonal format delivers lot-to-lot consistency for reproducible signal in fixed paraffin-embedded sections and whole-cell lysate preparations, and the unconjugated presentation allows laboratories to pair the reagent with their preferred secondary detection chemistry, including HRP, biotin, or fluorescent labels.