Anti-Cyclooxygenase 1 Antibody

Primary Polyclonal Antibody for COX-1 Research

Raised in rabbit and supplied by Antibodies.com, this unconjugated polyclonal antibody selectively targets Cyclooxygenase 1 (COX-1), the constitutive prostaglandin-endoperoxide synthase that maintains baseline thromboxane and cytoprotective prostaglandin synthesis across many tissues. The reagent is provided as 100 µl of stock solution and is validated for Western blot (WB) and immunohistochemistry (IHC) applications on human samples.

COX-1 expression is studied frequently in the gastrointestinal mucosa, in platelets, and in cancer models where researchers compare constitutive versus inducible cyclooxygenase activity or evaluate the off-target effects of COX-2-selective inhibitors. The antibody gives investigators a tool to probe baseline prostaglandin pathways in cell culture lysates and fixed tissue sections, supporting pharmacology, inflammation, and oncology workflows.

Polyclonal rabbit host and unconjugated format allow flexible secondary antibody selection, and reproducible signal has been demonstrated across experimental replicates. Detailed protocol notes accompany the vial to streamline both protein detection by WB and localization studies by IHC.