Anti-Cyclin G Antibody

This polyclonal antibody from Antibodies.com targets Cyclin G, a regulatory cyclin family member involved in cell cycle progression and checkpoint control. Cyclin G acts as a transcriptional target and downstream effector of p53 signaling, and it is frequently examined in DNA damage response studies, hepatocyte biology research, and oncology investigations where altered expression patterns have been reported in several tumor types.

Supplied as 100 µl of unconjugated polyclonal antiserum raised in rabbit, this reagent is validated for western blot (WB) and immunohistochemistry (IHC) workflows. The antibody was raised against Cyclin G and shows reactivity with Human, Mouse, and Rat samples, supporting comparative studies across multiple model organisms. The polyclonal format enables recognition of distinct epitopes on the Cyclin G target, which can be useful when probing different isoforms or post-translationally modified forms encountered in cell cycle and stress response research.

Storage recommendation is refrigeration in working aliquots to preserve antibody activity across repeated experimental cycles. For detection, researchers typically pair this primary reagent with appropriate rabbit-reactive secondary antibodies, such as HRP conjugates for chemiluminescent western blot or biotinylated systems for IHC tissue staining. Investigators focused on cyclin-dependent kinase regulation, p53-mediated transcriptional programs, and cell cycle arrest pathways will find this reagent a versatile tool for both protein expression quantification and tissue localization studies.