Anti-Cyclin E1 Antibody

Cyclin E1 partners with CDK2 to drive the G1/S transition and initiation of DNA replication, and this unconjugated rabbit polyclonal antibody from Antibodies.com provides a tool for tracking that regulator in cells and tissues. Supplied as a 100 µl vial, the reagent is validated for western blot, immunohistochemistry, and immunofluorescence workflows.

The antibody reacts with Cyclin E1 from human, mouse, and rat samples, supporting translational studies that span cancer cell line models to rodent tissue. Cyclin E1 dysregulation, including CCNE1 genomic amplification and accumulation of low-molecular-weight isoforms, is a documented feature in breast, ovarian, and endometrial carcinomas, giving this reagent clear relevance to cell-cycle and tumor biology research. Polyclonal recognition of multiple epitopes on the full-length protein aids detection across conditions where post-translational processing or isoform variation may occur.

Store refrigerated in working aliquots and protect from light; avoid repeated freeze-thaw cycles. The reagent is intended for research use only.