Anti-Cyclin D2 Antibody

Cyclin D2 serves as a regulatory subunit of cyclin-dependent kinase complexes (primarily CDK4 and CDK6), driving the G1 to S phase transition in actively dividing cells. This polyclonal reagent from Antibodies.com recognizes the Cyclin D2 protein in human, mouse, and rat samples and is supplied at 1 mg/ml in PBS supplemented with 0.1% sodium azide and 50% glycerol, which acts as a cryoprotective stabilizer for freezer storage.

Raised in rabbit and provided unconjugated, the antibody gives researchers flexibility to pair it with their preferred secondary conjugates for western blot, immunofluorescence, and immunohistochemistry workflows. The 100 µl volume supports multiple replicate experiments, making it practical for studies tracking endogenous Cyclin D2 expression across normal tissues and transformed specimens, including B-cell lineage cells, ovarian tissue, and developing neurons where this cyclin plays documented regulatory roles.

For best results, store the vial at -20 degrees C in working aliquots; this approach preserves antibody activity across repeated freeze-thaw cycles and minimizes ice crystal damage to the immunoglobulin during long-term storage.