Anti-Cyclin D1 Antibody

Primary antibody option for Cyclin D1 research from Antibodies.com. This rabbit polyclonal reagent targets the cyclin D1 protein, a key regulator of the G1 to S phase transition in the cell cycle. Conjugation is unconjugated, the vial is supplied at 100 µl, and reactivity is confirmed for human, mouse, and rat samples, making it useful across a broad range of cell cycle and oncology workflows.

Validated applications include western blot, immunohistochemistry, and ELISA. Researchers commonly apply this antibody to studies of cyclin D1 overexpression in breast cancer and to mantle cell lymphoma diagnostics, where cyclin D1 nuclear staining is a defining immunohistochemical feature. The polyclonal format provides recognition of multiple epitopes on the CCND1-encoded protein, which is helpful when working with samples that show variable expression or differing fixation conditions.

For western blot, the antibody detects the ~36 kDa cyclin D1 band. Aliquot upon receipt and store refrigerated to preserve activity across repeated freeze-thaw cycles. This reagent is intended for research use only and fits laboratories investigating proliferation, tumor biology, and cell cycle checkpoint control.