Anti-Cyclin A1 Antibody

This rabbit polyclonal antibody from Antibodies.com is raised against Cyclin A1, a cyclin family member that drives the G1/S and G2/M phase transitions of the eukaryotic cell cycle by partnering with CDK2 and CDK1. Unlike the ubiquitously expressed Cyclin A2, Cyclin A1 shows a more restricted tissue distribution, with notable expression in meiotic germ cells during spermatogenesis and recurrent reactivation in acute myeloid leukemia and certain solid tumors, making it a target of interest for cell cycle, reproductive biology, and oncology research programs.

Supplied as 100 µL of unconjugated antiserum, the reagent is validated for Western blot, immunohistochemistry, and ELISA workflows across human, mouse, and rat samples. Polyclonal immunity provides multi-epitope recognition of native and denatured Cyclin A1, supporting both endpoint assays and microscopy-based localization in fixed tissue sections.