Anti-CXCR-3 Antibody

CXCR3 is a G protein-coupled chemokine receptor that binds CXCL9, CXCL10, and CXCL11, directing activated T lymphocytes and natural killer cells toward inflamed tissue and tumor microenvironments. This unconjugated rabbit polyclonal reagent from Antibodies.com detects the receptor in human, mouse, and rat specimens, supporting investigations of Th1 effector trafficking, autoimmune inflammation, graft rejection, and tumor-infiltrating lymphocyte biology.

Supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the antibody drops directly into standard western blot and immunohistochemistry protocols without further dilution. The 100 µl vial yields ample material for dozens of membrane blots or several hundred paraffin-embedded tissue sections. Polyclonal coverage across multiple epitopes of CXCR3 helps resolve low-abundance receptor expression on effector T cells and NK cell populations, where the molecule commonly marks functional activation and tissue-homing capacity.

Storage at -20°C in the glycerol buffer preserves binding activity through repeated freeze-thaw cycles, allowing longitudinal panels across matched patient samples or serial time-course experiments. Cross-species reactivity to Human, Mouse, and Rat enables direct comparison of murine disease models with human biopsy material, while the unconjugated format gives researchers freedom to pair the antibody with HRP, biotin, or fluorescent secondaries matched to their detection platform.