Anti-CWC27 Antibody

The CWC27 spliceosome-associated protein homolog is a nuclear factor involved in the catalytic steps of pre-mRNA splicing, where it functions as part of the multi-subunit spliceosome complex. Rabbit polyclonal antibodies raised against human CWC27 enable detection of this protein in research samples using standard Western blot and immunohistochemistry workflows on human tissue. This unconjugated antibody is supplied in a 100 µl vial by Antibodies.com, with reactivity confirmed for human samples.

CWC27 has attracted research attention because loss-of-function variants in the gene have been linked to autosomal recessive retinal dystrophy and syndromic forms involving intellectual disability, making reliable antibodies useful for studies of splicing factor biology and disease-associated tissue. The polyclonal host rabbit origin gives a broader epitope recognition profile compared with monoclonal reagents, which is often advantageous for detecting endogenous CWC27 across different expression levels in cell and tissue lysates.