Anti-CUL1 Antibody

From Antibodies.com, this rabbit polyclonal reagent targets Cullin-1 (CUL1), a scaffold component of SCF ubiquitin ligase complexes, and is raised against a recombinant human CUL1 immunogen that was affinity-purified to ensure specificity for the endogenous total CUL1 protein (synonyms: CUL-1, Cullin-1). Supplied at 1.0 mg/mL in 50 µL aliquots of unconjugated antibody, the formulation is phosphate-buffered saline at pH 7.4 (without Mg²⁺ or Ca²⁺) containing 150 mM NaCl, 0.02% sodium azide and 50% glycerol; the product is shipped at 4 °C and should be stored at –20 °C with freeze/thaw cycles avoided. The host species is rabbit and the clonality is polyclonal, so lot-to-lot variability is reduced through pooled immunogen affinity purification rather than a single clone or defined isotype. Validated applications on the supplier page are Western blot (WB) and immunocytochemistry/immunofluorescence (ICC/IF), and the antibody is reactive with human, mouse and rat samples, making it useful across standard mammalian cell and tissue workflows. Researchers should note that this reagent is supplied for research use only and is not intended for diagnostic or therapeutic applications. For laboratories running parallel blots and imaging experiments, the combination of a robust polyclonal response against total CUL1 with cross-species reactivity and a glycerol-containing buffer that preserves activity through repeated use provides flexibility for both short-term imaging and longer-term blotting studies.