Anti-CUL 2 Antibody

CUL 2 (Cullin 2) is a scaffold component of cullin-RING E3 ubiquitin ligase complexes, where it assembles with Elongin B, Elongin C, and a SOCS-box adaptor to drive targeted protein polyubiquitination. This unconjugated rabbit polyclonal antibody from Antibodies.com recognises the endogenous CUL 2 protein and has been validated for Western blot, immunohistochemistry, and immunofluorescence workflows across human, mouse, and rat samples, making it useful for studies of hypoxia signalling, VHL-mediated proteasomal targeting, and cell-cycle checkpoint control.

Each vial is supplied as 100 µl of affinity-purified antibody at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant, supporting short-term handling at room temperature. Because sodium azide is present, the reagent should not be applied directly to live-cell preparations without extensive washing, and azide-free aliquots should be reserved for any downstream in vivo work.