Anti-CTSF Antibody

Cathepsin F (CTSF) is a lysosomal cysteine protease of the papain family that participates in intracellular protein turnover, antigen processing in macrophages, and tissue-remodeling events linked to tumor invasion. This rabbit polyclonal reagent from Antibodies.com detects the human CTSF protein and is supplied as 100 µl of unconjugated IgG for use as a primary antibody in research applications.

The polyclonal format presents multiple epitopes on CTSF, useful when working with denatured samples for western blot or fixed tissue sections for IHC, where epitope masking is a common concern. Cathepsin F has been investigated in neurodegenerative disease models, cancer metastasis studies, and immune-cell function research, making reliable detection tools important across these fields.

Validated applications include WB for detecting CTSF expression across cell lysates, IHC for localizing the protease in tissue sections, and flow cytometry for surface or intracellular staining. The unconjugated format allows researchers to pair the reagent with custom secondary conjugates, including HRP, fluorophores, or biotin. Refrigerate the antibody upon arrival and avoid repeated freeze-thaw cycles; aliquoting upon first use is recommended to preserve long-term activity.