Anti-CTH Antibody

Cystathionine gamma-lyase (CTH) sits at the final step of the transsulfuration pathway, where it converts cystathionine into cysteine, α-ketobutyrate, and ammonia, while also serving as a major source of endogenous hydrogen sulfide (H2S) in mammalian tissues. This rabbit polyclonal antibody from Antibodies.com is raised against CTH and validated for Western blot on samples derived from human, mouse, and rat sources, supporting studies of H2S signaling, redox balance, and transsulfuration metabolism.

The unconjugated reagent is supplied at 1 mg/ml in phosphate buffered saline (PBS) containing 15 mM sodium azide at approximately pH 7.2, packaged in a 50 µl vial sized for multiple immunoblotting runs. The polyclonal format increases the likelihood of recognizing multiple epitopes on the CTH protein, which strengthens signal robustness across varied expression levels in cell lysates and tissue homogenates.

For routine use, store refrigerated and protect from light; for longer retention of activity, aliquot and freeze at -20 °C, avoiding repeated freeze-thaw cycles. The included sodium azide acts as a microbial preservative, so handle the vial accordingly during downstream applications. Researchers working in cardiovascular, hepatic, or neurological contexts frequently turn to this reagent when probing CTH band patterns in cellular and tissue-level models.