Anti-CST1 Antibody

Raised in rabbit against the Cystatin SN protein target, this unconjugated polyclonal reagent from Antibodies.com is verified for western blot and immunohistochemistry on human-derived samples, supporting immunoblotting of cell or tissue lysates as well as chromogenic staining of formalin-fixed paraffin-embedded sections. The antibody recognizes endogenous CST1, a secreted type-2 cysteine protease inhibitor implicated in epithelial barrier function and reported as a dysregulated marker in gastric, colorectal, and other solid-tumor contexts, where elevated expression has been linked to tumor progression and immune-microenvironment remodeling.

The reagent is supplied as a 100 µL aliquot at 1 mg/mL in PBS with 0.1% sodium azide and 50% glycerol as a cryoprotectant. Store at -20 °C and partition into working aliquots to limit freeze-thaw cycles. Reactivity has been confirmed for Human, supporting profiling of CST1 expression across epithelial tissues, validating transcriptomic and proteomic datasets at the protein level, and exploring cysteine-protease-pathway signaling in inflammation and oncology research. Pairing with appropriate secondary detection reagents enables signal development in standard chemiluminescent and chromogenic workflows.