Anti-CSNK2B Antibody

Raised in rabbit against the CSNK2B regulatory subunit of casein kinase II, this unconjugated polyclonal IgG primary reagent is supplied as a 200 µl liquid aliquot for laboratory research use. The antibody recognizes an epitope conserved across human, mouse, and rat CK2β, supporting reproducible detection in western blot and immunohistochemistry workflows on cultured cells and fixed tissue sections.

Casein kinase II is a tetrameric serine/threonine kinase composed of two catalytic α/α′ subunits and two regulatory β subunits encoded by CSNK2B. The β subunit stabilizes the holoenzyme, modulates substrate selectivity, and contributes to cell cycle progression, Wnt signaling, and ribosome biogenesis, with loss-of-function mutations linked to Poirier-Bienvenu neurodevelopmental syndrome and dysregulated activity reported in several solid tumors.

This unconjugated reagent from Antibodies.com should be stored refrigerated in the supplied vial; for longer-term storage, aliquot and freeze, avoiding repeated freeze-thaw cycles. The unconjugated format allows flexible pairing with HRP-, biotin-, or fluorophore-conjugated secondary antibodies depending on the detection chemistry required.